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RAB1A Probably required for transit of protein from the ER through Golgi compartment. Binds GTP and GDP and possesses intrinsic GTPase activity. Belongs to the small GTPase superfamily. Rab family. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: G protein; G protein, monomeric; G protein, monomeric, Rab
Chromosomal Location of Human Ortholog: 2p14
Cellular Component: cytosol; endoplasmic reticulum membrane; Golgi apparatus; Golgi membrane
Molecular Function: cadherin binding; GTPase activity; protein binding
Biological Process: autophagic vacuole formation; autophagy; cell migration; COPII coating of Golgi vesicle; defense response to bacterium; endocytosis; ER to Golgi vesicle-mediated transport; Golgi organization and biogenesis; growth hormone secretion; post-translational protein modification; retrograde vesicle-mediated transport, Golgi to ER; vesicle transport along microtubule; vesicle-mediated transport; virus assembly
Reference #:  P62820 (UniProtKB)
Alt. Names/Synonyms: DKFZp564B163; GTP binding protein Rab1a; Rab GTPase YPT1 homolog; RAB1; RAB1, member RAS oncogene family; RAB1A; RAB1A, member RAS oncogene family; Ras-related protein Rab-1A; YPT1; YPT1-related protein
Gene Symbols: RAB1A
Molecular weight: 22,678 Da
Basal Isoelectric point: 5.93  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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