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Protein Page:

N-Myc a proto-oncogenic transcription factor. Plays a role in cell proliferation, apoptosis and in the development of human tumors. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Oncoprotein; Transcription factor
Chromosomal Location of Human Ortholog: 2p24.3
Cellular Component: chromatin; nucleolus; nucleus
Molecular Function: DNA binding; protein binding
Biological Process: positive regulation of transcription, DNA-dependent; regulation of transcription from RNA polymerase II promoter
Disease: Feingold Syndrome 1; Tracheoesophageal Fistula With Or Without Esophageal Atresia
Reference #:  P04198 (UniProtKB)
Alt. Names/Synonyms: BHLHE37; Class E basic helix-loop-helix protein 37; MODED; MYCN; N-myc; N-myc proto-oncogene protein; neuroblastoma MYC oncogene; neuroblastoma-derived v-myc avian myelocytomatosis viral related oncogene; NMYC; ODED; oncogene NMYC; pp65/67; v-myc avian myelocytomatosis viral related oncogene, neuroblastoma derived; v-myc myelocytomatosis viral related oncogene, neuroblastoma derived (avian)
Gene Symbols: MYCN
Molecular weight: 49,561 Da
Basal Isoelectric point: 5.45  Predict pI for various phosphorylation states
CST Pathways:  Growth And Differentiation Control by MAPKs
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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