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ARSA
Hydrolyzes cerebroside sulfate. Belongs to the sulfatase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 3.1.6.8; Hydrolase; Lipid Metabolism - sphingolipid |
| Chromosomal Location of human Ortholog: 22q13.33 |
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Cellular Component:
azurophil granule lumen; endoplasmic reticulum lumen; extracellular region; lysosomal lumen; lysosome
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Molecular Function:
arylsulfatase activity; calcium ion binding; cerebroside-sulfatase activity; protein binding; sulfuric ester hydrolase activity
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Biological Process:
lipid metabolic process
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Disease: Metachromatic Leukodystrophy
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Reference #:
P15289
(UniProtKB)
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Alt. Names/Synonyms: ARSA; Arylsulfatase A; Arylsulfatase A component B; Arylsulfatase A component C; ASA; Cerebroside-sulfatase; epididymis secretory sperm binding protein; MLD
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Gene Symbols: ARSA
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Molecular weight:
53,588 Da
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Basal Isoelectric point:
5.65
Predict pI for various phosphorylation states
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