MYO1B Motor protein that may participate in process critical to neuronal development and function such as cell migration, neurite outgrowth and vesicular transport. Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Myosin family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Actin-binding; Motility/polarity/chemotaxis; Motor
Chromosomal Location of Human Ortholog: 2q32.3
Cellular Component:  actin filament; apical part of cell; brush border; cell periphery; cytoplasm; early endosome; endosome membrane; filopodium; myosin complex; perinuclear region of cytoplasm; plasma membrane
Molecular Function:  actin filament binding; actin-dependent ATPase activity; ATP binding; calmodulin binding; microfilament motor activity; phosphatidylinositol-3,4,5-trisphosphate binding; phosphatidylinositol-4,5-bisphosphate binding
Biological Process:  actin filament bundle assembly; actin filament organization; actin filament-based movement; post-Golgi vesicle-mediated transport
Reference #:  O43795 (UniProtKB)
Alt. Names/Synonyms: MMI-alpha; MMIa; MYH-1c; MYO1B; MYO1B variant protein; Myosin I alpha; myosin IB; myosin-I alpha; Myosin-Ib; myr1; Unconventional myosin-Ib
Gene Symbols: MYO1B
Molecular weight: 131,985 Da
Basal Isoelectric point: 9.43  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein