TAS2R40 Gustducin-coupled receptor implicated in the perception of bitter compounds in the oral cavity and the gastrointestinal tract. Signals through PLCB2 and the calcium-regulated cation channel TRPM5. Belongs to the G-protein coupled receptor T2R family. Expressed in subsets of taste receptor cells of the tongue and exclusively in gustducin-positive cells. Note: This description may include information from UniProtKB.
Protein type: GPCR, T2R family; Membrane protein, integral; Membrane protein, multi-pass; Receptor, GPCR
Chromosomal Location of Human Ortholog: 7q34
Cellular Component:  integral component of membrane; plasma membrane
Molecular Function:  bitter taste receptor activity; G protein-coupled receptor activity
Biological Process:  detection of chemical stimulus involved in sensory perception of bitter taste; G protein-coupled receptor signaling pathway
Reference #:  P59535 (UniProtKB)
Alt. Names/Synonyms: G protein-coupled receptor 60; G-protein coupled receptor 60; GPR60; MGC126844; MGC126846; T2R40; T2R58; TAS2R40; Taste receptor type 2 member 40; Taste receptor type 2 member 58; taste receptor, type 2, member 40
Gene Symbols: TAS2R40
Molecular weight: 36,812 Da
Basal Isoelectric point: 9.95  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene