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ERP29
Does not seem to be a disulfide isomerase. Plays an important role in the processing of secretory proteins within the endoplasmic reticulum (ER), possibly by participating in the folding of proteins in the ER. Ubiquitous. Mostly expressed in secretory tissues. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Chaperone |
| Chromosomal Location of human Ortholog: 12q24.13 |
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Cellular Component:
cell surface; endoplasmic reticulum; endoplasmic reticulum lumen; melanosome; smooth endoplasmic reticulum; transport vesicle
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Molecular Function:
protein binding; protein disulfide isomerase activity; protein homodimerization activity; protein-folding chaperone binding
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Biological Process:
intracellular protein transport; negative regulation of gene expression; negative regulation of protein secretion; positive regulation of gene expression; positive regulation of MAP kinase activity; positive regulation of protein phosphorylation; protein folding; protein secretion; protein unfolding; regulation of endoplasmic reticulum stress-induced intrinsic apoptotic signaling pathway
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Reference #:
P30040
(UniProtKB)
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Alt. Names/Synonyms: C12orf8; endoplasmic reticulum lumenal protein ERp28; endoplasmic reticulum protein 29; Endoplasmic reticulum resident protein 28; Endoplasmic reticulum resident protein 29; Endoplasmic reticulum resident protein 31; epididymis secretory protein Li 107; ERP28; ERP29; ERp31; HEL-S-107; PDI-DB; PDIA9; protein disulfide isomerase family A, member 9
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Gene Symbols: ERP29
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Molecular weight:
28,993 Da
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Basal Isoelectric point:
6.77
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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