ADAMTS15
Expressed in fetal liver and kidney, but not in any of the adult tissues examined. Note: This description may include information from UniProtKB.
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Protein type: EC 3.4.24.-; Extracellular matrix; Motility/polarity/chemotaxis; Protease; Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 11q24.3 |
Cellular Component:
cell surface; collagen-containing extracellular matrix; extracellular matrix; extracellular space
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Molecular Function:
endopeptidase activity; extracellular matrix binding; heparin binding; metalloendopeptidase activity; zinc ion binding
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Biological Process:
extracellular matrix disassembly; extracellular matrix organization; myoblast fusion; proteolysis
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Disease: Arthrogryposis, Distal, Type 12
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Reference #:
Q8TE58
(UniProtKB)
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Alt. Names/Synonyms: A disintegrin and metalloproteinase with thrombospondin motifs 15; a disintegrin-like and metalloprotease (reprolysin type) with thrombospondin type 1 motif, 15, preproprotein; ADAM metallopeptidase with thrombospondin type 1 motif 15; ADAM metallopeptidase with thrombospondin type 1 motif, 15; ADAM-TS 15; ADAM-TS15; ADAMTS-15; ADAMTS15; ATS15; metalloprotease disintegrin 15 with thrombospondin domains; MGC126403
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Gene Symbols: ADAMTS15
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Molecular weight:
103,287 Da
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Basal Isoelectric point:
8.94
Predict pI for various phosphorylation states
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