PDCD11 Essential for the generation of mature 18S rRNA, specifically necessary for cleavages at sites A0, 1 and 2 of the 47S precursor. Directly interacts with U3 snoRNA. Involved in the biogenesis of rRNA. Note: This description may include information from UniProtKB.
Protein type: Nucleolus; RNA-binding
Chromosomal Location of Human Ortholog: 10q24.33
Cellular Component:  cytosol; nucleoplasm; nucleus
Molecular Function:  protein binding; transcription factor binding
Biological Process:  mRNA processing; rRNA processing
Reference #:  Q14690 (UniProtKB)
Alt. Names/Synonyms: ALG-4; ALG4; apoptosis-linked gene 4; KIAA0185; NF-kappa-B-binding protein; NFBP; PDCD11; programmed cell death 11; Programmed cell death protein 11; Protein RRP5 homolog; RRP5
Gene Symbols: PDCD11
Molecular weight: 208,701 Da
Basal Isoelectric point: 8.99  Predict pI for various phosphorylation states
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PDCD11

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  CCLE  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene