SLAMF6 Triggers cytolytic activity only in natural killer cells (NK) expressing high surface densities of natural cytotoxicity receptors. 3 isoforms of the human protein are produced by alternative splicing. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Receptor, misc.
Chromosomal Location of Human Ortholog: 1q23.2-q23.3
Cellular Component:  integral component of membrane; plasma membrane
Molecular Function:  protein binding
Biological Process:  innate immune response; positive regulation of interferon-gamma production; positive regulation of interleukin-17 production; positive regulation of natural killer cell mediated cytotoxicity; regulation of immune response; T-helper 17 cell lineage commitment
Reference #:  Q96DU3 (UniProtKB)
Alt. Names/Synonyms: Activating NK receptor; KALI; KALIb; Ly108; MGC104953; natural killer-, T- and B-cell antigen; NK-T-B-antigen; NTB-A; NTBA; NTBA receptor; SF2000; SLAF6; SLAM family member 6; SLAMF6
Gene Symbols: SLAMF6
Molecular weight: 37,345 Da
Basal Isoelectric point: 6.32  Predict pI for various phosphorylation states
Protein-Specific Antibodies or siRNAs from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein