GKN1 Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. Belongs to the gastrokine family. Expressed in stomach. No expression is detected in cancer tissue or gastric cancer cell lines. Note: This description may include information from UniProtKB.
Protein type: Secreted; Secreted, signal peptide
Chromosomal Location of human Ortholog: 2p13.3
Cellular Component:  extracellular region; extracellular space; Golgi apparatus; secretory granule
Molecular Function:  growth factor activity; protein binding
Biological Process:  digestion; positive regulation of cell division; positive regulation of cell population proliferation; regulation of cell population proliferation; signal transduction
Reference #:  Q9NS71 (UniProtKB)
Alt. Names/Synonyms: 18 kDa antrum mucosa protein; AMP-18; AMP18; BRICD1; BRICHOS domain containing 1; CA11; FOV; foveolin; gastrokine 1; Gastrokine-1; GKN1; MGC70354; Protein CA11
Gene Symbols: GKN1
Molecular weight: 20,331 Da
Basal Isoelectric point: 5.64  Predict pI for various phosphorylation states
Select Structure to View Below

GKN1

Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein