GKN1
Has mitogenic activity and may be involved in maintaining the integrity of the gastric mucosal epithelium. Belongs to the gastrokine family. Expressed in stomach. No expression is detected in cancer tissue or gastric cancer cell lines. Note: This description may include information from UniProtKB.
|
Protein type: Secreted; Secreted, signal peptide |
Chromosomal Location of human Ortholog: 2p13.3 |
Cellular Component:
extracellular region; extracellular space; Golgi apparatus; secretory granule
|
Molecular Function:
growth factor activity; protein binding
|
Biological Process:
digestion; positive regulation of cell division; positive regulation of cell population proliferation; regulation of cell population proliferation; signal transduction
|
Reference #:
Q9NS71
(UniProtKB)
|
Alt. Names/Synonyms: 18 kDa antrum mucosa protein; AMP-18; AMP18; BRICD1; BRICHOS domain containing 1; CA11; FOV; foveolin; gastrokine 1; Gastrokine-1; GKN1; MGC70354; Protein CA11
|
Gene Symbols: GKN1
|
Molecular weight:
20,331 Da
|
Basal Isoelectric point:
5.64
Predict pI for various phosphorylation states
|