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RBM7
Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. Possible involved in germ cell RNA processing and meiosis. Ubiquitous. Note: This description may include information from UniProtKB.
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| Protein type: RNA-binding |
| Chromosomal Location of Human Ortholog: 9|9 A5.3 |
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Cellular Component:
nucleoplasm; nucleus
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Molecular Function:
nucleic acid binding; RNA binding; single-stranded RNA binding
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Biological Process:
meiotic cell cycle; regulation of alternative mRNA splicing, via spliceosome
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Reference #:
Q9CQT2
(UniProtKB)
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Alt. Names/Synonyms: 1200007M24Rik; 1500011D06Rik; AU041934; AW554393; Rbm7; RNA binding motif protein 7; RNA-binding motif protein 7; RNA-binding protein 7
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Gene Symbols: Rbm7
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Molecular weight:
30,148 Da
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Basal Isoelectric point:
9.37
Predict pI for various phosphorylation states
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