RBM7 Subunit of the trimeric nuclear exosome targeting (NEXT) complex, a complex that directs a subset of non-coding short-lived RNAs for exosomal degradation. The RNA exosome is fundamental for the degradation of RNA in eukaryotic nuclei. Substrate targeting is facilitated by its cofactor MTREX, which links to RNA-binding protein adapters. Possible involved in germ cell RNA processing and meiosis. Ubiquitous. Note: This description may include information from UniProtKB.
Protein type: RNA-binding
Chromosomal Location of mouse Ortholog: 9|9 A5.3
Cellular Component:  nucleoplasm; nucleus
Molecular Function:  14-3-3 protein binding; nucleic acid binding; pre-mRNA intronic binding; protein binding; RNA binding; single-stranded RNA binding; snRNA binding
Biological Process:  meiotic cell cycle; regulation of alternative mRNA splicing, via spliceosome; snRNA catabolic process
Reference #:  Q9CQT2 (UniProtKB)
Alt. Names/Synonyms: 1200007M24Rik; 1500011D06Rik; AU041934; AW554393; Rbm7; RNA binding motif protein 7; RNA-binding motif protein 7; RNA-binding protein 7
Gene Symbols: Rbm7
Molecular weight: 30,148 Da
Basal Isoelectric point: 9.37  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein