ZDHHC8
Palmitoyltransferase involved in glutamatergic transmission. Mediates palmitoylation of ABCA1. Belongs to the DHHC palmitoyltransferase family. ERF2/ZDHHC9 subfamily. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
|
Protein type: EC 2.3.1.225; Membrane protein, integral; Membrane protein, multi-pass; Transferase |
Chromosomal Location of mouse Ortholog: 16 A3|16 11.29 cM |
Cellular Component:
Golgi apparatus; membrane; mitochondrion; perinuclear region of cytoplasm
|
Molecular Function:
acyltransferase activity; palmitoyltransferase activity; protein binding; protein-cysteine S-palmitoyltransferase activity; transferase activity
|
Biological Process:
locomotory behavior; peptidyl-L-cysteine S-palmitoylation; positive regulation by host of viral process; positive regulation of cholesterol efflux; protein palmitoylation
|
Reference #:
Q5Y5T5
(UniProtKB)
|
Alt. Names/Synonyms: D16H22S1738E; DHHC-8; DHHC-containing protein 8; E330009O14Rik; MGC103030; MGC118171; MGC7847; Op53c; Op53c05; Palmitoyltransferase ZDHHC8; Probable palmitoyltransferase ZDHHC8; ZDHC8; Zdhhc8; ZDHHCL1; Zinc finger DHHC domain-containing protein 8; zinc finger, DHHC domain containing 8
|
Gene Symbols: Zdhhc8
|
Molecular weight:
82,031 Da
|
Basal Isoelectric point:
9.48
Predict pI for various phosphorylation states
|