FBP1 Regulates MYC expression by binding to a single-stranded far-upstream element (FUSE) upstream of the MYC promoter. May act both as activator and repressor of transcription. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Motility/polarity/chemotaxis; RNA splicing; RNA-binding; Transcription factor
Chromosomal Location of Human Ortholog: 3 H3|3 77.05 cM
Cellular Component:  nucleoplasm; nucleus; synapse
Molecular Function:  DNA binding; DNA-binding transcription activator activity, RNA polymerase II-specific; nucleic acid binding; protein binding; RNA binding; sequence-specific double-stranded DNA binding
Biological Process:  developmental cell growth; hematopoietic stem cell proliferation; positive regulation of gene expression; positive regulation of Schwann cell migration; regulation of transcription by RNA polymerase II; regulation of transcription, DNA-templated; somatic stem cell division
Reference #:  Q91WJ8 (UniProtKB)
Alt. Names/Synonyms: 9530027K12Rik; D3Ertd330e; far upstream element (FUSE) binding protein 1; far upstream element (FUSE) binding protein 4; Far upstream element-binding protein 1; FBP; Fubp; Fubp1; Fubp4; FUSE-binding protein 1
Gene Symbols: Fubp1
Molecular weight: 68,540 Da
Basal Isoelectric point: 7.73  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene