NTCP The hepatic sodium/bile acid uptake system exhibits broad substrate specificity and transports various non-bile acid organic compounds as well. It is strictly dependent on the extracellular presence of sodium. (Microbial infection) Acts as a receptor for hepatitis B virus. Belongs to the bile acid:sodium symporter (BASS) (TC 2.A.28) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass; Transporter
Chromosomal Location of Human Ortholog: 12 C3-D1|12 37.21 cM
Cellular Component:  basolateral plasma membrane; integral component of membrane; membrane
Molecular Function:  bile acid transmembrane transporter activity; bile acid:sodium symporter activity; symporter activity
Biological Process:  bile acid and bile salt transport; ion transport; sodium ion transport
Reference #:  O08705 (UniProtKB)
Alt. Names/Synonyms: bile acid cotransporting polypeptide; Na(+)/bile acid cotransporter; Na(+)/taurocholate transport protein; Ntcp; Slc10a1; sodium bile acid cotransporting polypeptide; sodium-taurocholate cotransporting polypeptide; Sodium/bile acid cotransporter; Sodium/taurocholate cotransporting polypeptide; solute carrier family 10 (sodium/bile acid cotransporter family), member 1; Solute carrier family 10 member 1
Gene Symbols: Slc10a1
Molecular weight: 39,413 Da
Basal Isoelectric point: 9.2  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene