DDA1 May be involved in ubiquitination and subsequent proteasomal degradation of target proteins. Component of the DDD-E2 complexes which may provide a platform for interaction with CUL4A and WD repeat proteins. Belongs to the DDA1 family. Note: This description may include information from UniProtKB.
Protein type: Autophagy; Ubiquitin conjugating system
Chromosomal Location of human Ortholog: 19p13.11
Cellular Component:  Cul4-RING E3 ubiquitin ligase complex; nucleoplasm
Molecular Function:  protein binding
Biological Process:  positive regulation of proteasomal ubiquitin-dependent protein catabolic process; protein polyubiquitination
Reference #:  Q9BW61 (UniProtKB)
Alt. Names/Synonyms: C19orf58; cross-immune reaction antigen PCIA1; DDA1; DET1 and DDB1 associated 1; DET1- and DDB1-associated protein 1; MGC2594; PCIA-1; PCIA1; Placenta cross-immune reaction antigen 1
Gene Symbols: DDA1
Molecular weight: 11,835 Da
Basal Isoelectric point: 8.73  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene