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eIF2B-beta
Catalyzes the exchange of eukaryotic initiation factor 2-bound GDP for GTP. Belongs to the eIF-2B alpha/beta/delta subunits family. Note: This description may include information from UniProtKB.
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| Protein type: Cell development/differentiation; GEF; GEF, misc.; RNA-binding; Translation |
| Chromosomal Location of Human Ortholog: 12|12 D1 |
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Cellular Component:
axon; cytoplasm; eukaryotic translation initiation factor 2B complex
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Molecular Function:
ATP binding; GTP binding; translation initiation factor activity
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Biological Process:
cellular metabolic process; central nervous system development; myelination; oligodendrocyte development; ovarian follicle development; positive regulation of axon extension; regulation of translational initiation; response to glucose; response to heat; response to peptide hormone; T cell receptor signaling pathway; translation; translational initiation
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Reference #:
Q99LD9
(UniProtKB)
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Alt. Names/Synonyms: AA409345; C85417; EI2BB; eIF-2B GDP-GTP exchange factor subunit beta; EIF-2Bbe; EIF-2Bbeta; EIF2; EIF2B; eIF2B-beta; Eif2b2; eukaryotic translation initiation factor 2B, subunit 2 beta; Translation initiation factor eIF-2B subunit beta
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Gene Symbols: Eif2b2
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Molecular weight:
38,898 Da
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Basal Isoelectric point:
5.82
Predict pI for various phosphorylation states
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CST Pathways:
Translation: eIF2
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Translational Control
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