NDUFS4 Accessory subunit of the mitochondrial membrane respiratory chain NADH dehydrogenase (Complex I), that is believed not to be involved in catalysis. Complex I functions in the transfer of electrons from NADH to the respiratory chain. The immediate electron acceptor for the enzyme is believed to be ubiquinone. Belongs to the complex I NDUFS4 subunit family. Note: This description may include information from UniProtKB.
Protein type: EC; EC; Energy Metabolism - oxidative phosphorylation; Mitochondrial; Oxidoreductase
Chromosomal Location of mouse Ortholog: 13|13 D2.2
Cellular Component:  membrane; mitochondrial inner membrane; mitochondrial respiratory chain complex I; mitochondrion; respiratory chain
Molecular Function:  NADH dehydrogenase (ubiquinone) activity; oxidoreductase activity, acting on NAD(P)H
Biological Process:  brain development; cAMP-mediated signaling; cellular respiration; electron transport chain; mitochondrial respiratory chain complex I assembly; positive regulation of fibroblast proliferation; reactive oxygen species metabolic process; regulation of protein phosphorylation; response to cAMP
Reference #:  Q9CXZ1 (UniProtKB)
Alt. Names/Synonyms: 6720411N02Rik; C1-18k; CI-18 kDa; CI-AQDQ; Complex I-18 kDa; Complex I-AQDQ; NADH dehydrogenase (ubiquinone) Fe-S protein 4; NADH dehydrogenase [ubiquinone] iron-sulfur protein 4, mitochondrial; NADH-ubiquinone oxidoreductase 18 kDa subunit; NADH:ubiquinone oxidoreductase core subunit S4; Ndufs4; NDUS4
Gene Symbols: Ndufs4
Molecular weight: 19,785 Da
Basal Isoelectric point: 10  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  Reactome  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene