FBXL20 Substrate-recognition component of the SCF (SKP1-CUL1-F-box protein)-type E3 ubiquitin ligase complex. Role in neural transmission. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 17q12
Cellular Component:  cytosol; glutamatergic synapse; presynapse; Schaffer collateral - CA1 synapse
Molecular Function:  protein binding
Biological Process:  behavioral fear response; post-translational protein modification; protein polyubiquitination; regulation of protein catabolic process at presynapse, modulating synaptic transmission; regulation of synaptic vesicle exocytosis
Reference #:  Q96IG2 (UniProtKB)
Alt. Names/Synonyms: F-box and leucine-rich repeat protein 20; F-box and leucine-rich repeat protein 20 variant b; F-box protein FBL2; F-box/LRR-repeat protein 2-like; F-box/LRR-repeat protein 20; FBL2; Fbl20; FBXL20; FLJ21037; FXL20; MGC15482; SCR; SCRAPPER
Gene Symbols: FBXL20
Molecular weight: 48,423 Da
Basal Isoelectric point: 7.65  Predict pI for various phosphorylation states
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FBXL20

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein