ILF2 Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Essential for the efficient reshuttling of ILF3 (isoform 1 and isoform 2) into the nucleus. Note: This description may include information from UniProtKB.
Protein type: Nucleolus; RNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 3|3 F1
Cellular Component:  cytoplasm; nucleolus; nucleus; ribonucleoprotein complex
Molecular Function:  ATP binding; DNA binding; double-stranded RNA binding; RNA binding; transferase activity
Biological Process:  immune response; positive regulation of transcription, DNA-templated; transcription, DNA-templated
Reference #:  Q9CXY6 (UniProtKB)
Alt. Names/Synonyms: 6230405A16Rik; Ilf2; interleukin enhancer binding factor 2; Interleukin enhancer-binding factor 2; Nf45; Nuclear factor of activated T-cells 45 kDa; TEG-267; testis expressed gene 267; Tex261; Tex267
Gene Symbols: Ilf2
Molecular weight: 43,062 Da
Basal Isoelectric point: 5.19  Predict pI for various phosphorylation states
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ILF2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene