ILF2 Appears to function predominantly as a heterodimeric complex with ILF3. This complex may regulate transcription of the IL2 gene during T-cell activation. It can also promote the formation of stable DNA-dependent protein kinase holoenzyme complexes on DNA. Note: This description may include information from UniProtKB.
Protein type: Nucleolus; RNA-binding; Transcription, coactivator/corepressor
Chromosomal Location of Human Ortholog: 1q21.3
Cellular Component:  extracellular region; ficolin-1-rich granule lumen; nucleolus; nucleus; ribonucleoprotein complex; specific granule lumen; tertiary granule lumen
Molecular Function:  ATP binding; DNA binding; double-stranded RNA binding; protein binding; transferase activity
Biological Process:  neutrophil degranulation; positive regulation of transcription, DNA-templated; transcription, DNA-templated
Reference #:  Q12905 (UniProtKB)
Alt. Names/Synonyms: ILF2; interleukin enhancer binding factor 2, 45kDa; Interleukin enhancer-binding factor 2; MGC8391; NF45; Nuclear factor of activated T-cells 45 kDa; nuclear factor of activated T-cells, 45-kDa; PRO3063
Gene Symbols: ILF2
Molecular weight: 43,062 Da
Basal Isoelectric point: 5.19  Predict pI for various phosphorylation states
Select Structure to View Below

ILF2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene