FANCA DNA repair protein that may operate in a postreplication repair or a cell cycle checkpoint function. May be involved in interstrand DNA cross-link repair and in the maintenance of normal chromosome stability. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA repair, damage
Chromosomal Location of Human Ortholog: 8 E1|8 72.1 cM
Cellular Component:  cytoplasm; Fanconi anaemia nuclear complex; nucleus
Biological Process:  cellular response to DNA damage stimulus; DNA repair; female gonad development; interstrand cross-link repair; male gonad development; male meiotic nuclear division; regulation of CD40 signaling pathway; regulation of cell proliferation; regulation of DNA-binding transcription factor activity; regulation of inflammatory response; regulation of regulatory T cell differentiation
Reference #:  Q9JL70 (UniProtKB)
Alt. Names/Synonyms: AW208693; FACA; Fanca; Fanconi anemia group A protein homolog; Fanconi anemia, complementation group A; Protein FACA
Gene Symbols: Fanca
Molecular weight: 161,213 Da
Basal Isoelectric point: 6.83  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene