PSF2 The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. Belongs to the GINS2/PSF2 family. Note: This description may include information from UniProtKB.
Protein type: DNA replication
Chromosomal Location of human Ortholog: 16q24.1
Cellular Component:  CMG complex; GINS complex; nucleoplasm; nucleus
Molecular Function:  protein binding
Biological Process:  DNA unwinding involved in DNA replication; double-strand break repair via break-induced replication; positive regulation of DNA primase activity; positive regulation of DNA-directed DNA polymerase activity
Reference #:  Q9Y248 (UniProtKB)
Alt. Names/Synonyms: DNA replication complex GINS protein PSF2; GINS complex subunit 2; GINS complex subunit 2 (Psf2 homolog); GINS2; HSPC037; Pfs2; PSF2
Gene Symbols: GINS2
Molecular weight: 21,428 Da
Basal Isoelectric point: 5.29  Predict pI for various phosphorylation states
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PSF2

Protein Structure Not Found.


Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene