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PSF2
The GINS complex plays an essential role in the initiation of DNA replication, and progression of DNA replication forks. GINS complex seems to bind preferentially to single-stranded DNA. Belongs to the GINS2/PSF2 family. Note: This description may include information from UniProtKB.
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| Protein type: DNA replication |
| Chromosomal Location of human Ortholog: 16q24.1 |
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Cellular Component:
CMG complex; GINS complex; nucleoplasm; nucleus
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Molecular Function:
protein binding
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Biological Process:
DNA unwinding involved in DNA replication; double-strand break repair via break-induced replication; positive regulation of DNA primase activity; positive regulation of DNA-directed DNA polymerase activity
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Reference #:
Q9Y248
(UniProtKB)
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Alt. Names/Synonyms: DNA replication complex GINS protein PSF2; GINS complex subunit 2; GINS complex subunit 2 (Psf2 homolog); GINS2; HSPC037; Pfs2; PSF2
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Gene Symbols: GINS2
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Molecular weight:
21,428 Da
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Basal Isoelectric point:
5.29
Predict pI for various phosphorylation states
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