TGM5 Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes. Belongs to the transglutaminase superfamily. Transglutaminase family. Expressed in foreskin keratinocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: EC; Transferase
Chromosomal Location of Human Ortholog: 2|2 E5
Cellular Component:  cytoplasm
Molecular Function:  metal ion binding; protein-glutamine gamma-glutamyltransferase activity; transferase activity; transferase activity, transferring acyl groups
Biological Process:  peptide cross-linking
Reference #:  Q9D7I9 (UniProtKB)
Alt. Names/Synonyms: 2310007C07Rik; MGC143848; MGC143849; OTTMUSP00000017043; Protein-glutamine gamma-glutamyltransferase 5; TGase 5; TGase-5; Tgm5; TGMX; TGx; transglutaminase 5; Transglutaminase-5
Gene Symbols: Tgm5
Molecular weight: 81,014 Da
Basal Isoelectric point: 5.48  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene