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TGM5
Catalyzes the cross-linking of proteins and the conjugation of polyamines to proteins. Contributes to the formation of the cornified cell envelope of keratinocytes. Belongs to the transglutaminase superfamily. Transglutaminase family. Expressed in foreskin keratinocytes. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: EC 2.3.2.13; Transferase |
| Chromosomal Location of mouse Ortholog: 2|2 E5 |
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Cellular Component:
cytoplasm
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Molecular Function:
acyltransferase activity; metal ion binding; protein-glutamine gamma-glutamyltransferase activity; transferase activity
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Biological Process:
peptide cross-linking
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Reference #:
Q9D7I9
(UniProtKB)
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Alt. Names/Synonyms: 2310007C07Rik; MGC143848; MGC143849; OTTMUSP00000017043; Protein-glutamine gamma-glutamyltransferase 5; TGase 5; TGase-5; Tgm5; TGMX; TGx; transglutaminase 5; Transglutaminase-5
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Gene Symbols: Tgm5
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Molecular weight:
81,014 Da
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Basal Isoelectric point:
5.48
Predict pI for various phosphorylation states
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