MON1A Plays an important role in membrane trafficking through the secretory apparatus. Not involved in endocytic trafficking to lysosomes. Acts in concert with CCZ1, as a guanine exchange factor (GEF) for RAB7, promotes the exchange of GDP to GTP, converting it from an inactive GDP-bound form into an active GTP-bound form. Belongs to the MON1/SAND family. 5 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 3p21.31
Cellular Component:  cytosol; Mon1-Ccz1 complex
Molecular Function:  guanyl-nucleotide exchange factor activity; protein binding
Reference #:  Q86VX9 (UniProtKB)
Alt. Names/Synonyms: FLJ97088; MGC13272; MON1 homolog A (yeast); MON1 homolog A, secretory trafficking associated; MON1 secretory trafficking family member A; MON1A; SAND1; Vacuolar fusion protein MON1 homolog A
Gene Symbols: MON1A
Molecular weight: 62,131 Da
Basal Isoelectric point: 5.9  Predict pI for various phosphorylation states
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MON1A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene