ATASE In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. Ubiquitously expressed. Note: This description may include information from UniProtKB.
Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; EC; Nucleotide Metabolism - purine; Transferase
Chromosomal Location of human Ortholog: 4q12
Cellular Component:  cytosol
Molecular Function:  4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; metal ion binding
Biological Process:  'de novo' IMP biosynthetic process; animal organ regeneration; cellular response to drug; cellular response to insulin stimulus; G1/S transition of mitotic cell cycle; glutamine catabolic process; kidney development; lactation; maternal process involved in female pregnancy; nucleoside metabolic process; protein homotetramerization; purine nucleobase biosynthetic process; purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process
Reference #:  Q06203 (UniProtKB)
Alt. Names/Synonyms: Amidophosphoribosyltransferase; ATase; glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT; phosphoribosyl pyrophosphate amidotransferase; PPAT; PRAT; PUR1
Gene Symbols: PPAT
Molecular weight: 57,399 Da
Basal Isoelectric point: 6.3  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB