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ATASE
In the C-terminal section; belongs to the purine/pyrimidine phosphoribosyltransferase family. Ubiquitously expressed. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - alanine, aspartate and glutamate; EC 2.4.2.14; Nucleotide Metabolism - purine; Transferase |
| Chromosomal Location of human Ortholog: 4q12 |
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Cellular Component:
cytosol
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Molecular Function:
4 iron, 4 sulfur cluster binding; amidophosphoribosyltransferase activity; metal ion binding
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Biological Process:
'de novo' IMP biosynthetic process; animal organ regeneration; cellular response to drug; cellular response to insulin stimulus; G1/S transition of mitotic cell cycle; glutamine catabolic process; kidney development; lactation; maternal process involved in female pregnancy; nucleoside metabolic process; protein homotetramerization; purine nucleobase biosynthetic process; purine nucleotide biosynthetic process; purine ribonucleoside monophosphate biosynthetic process
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Reference #:
Q06203
(UniProtKB)
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Alt. Names/Synonyms: Amidophosphoribosyltransferase; ATase; glutamine phosphoribosylpyrophosphatate amidotransferase; Glutamine phosphoribosylpyrophosphate amidotransferase; glutamine PRPP amidotransferase; GPAT; phosphoribosyl pyrophosphate amidotransferase; PPAT; PRAT; PUR1
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Gene Symbols: PPAT
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Molecular weight:
57,399 Da
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Basal Isoelectric point:
6.3
Predict pI for various phosphorylation states
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