POM121C Essential component of the nuclear pore complex (NPC). The repeat-containing domain may be involved in anchoring components of the pore complex to the pore membrane. When overexpressed in cells induces the formation of cytoplasmic annulate lamellae (AL). Belongs to the POM121 family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral
Chromosomal Location of human Ortholog: 7q11.23
Cellular Component:  endoplasmic reticulum membrane; host cell; integral component of membrane; nuclear envelope; nuclear membrane
Molecular Function:  protein binding
Biological Process:  intracellular transport of virus; mRNA export from nucleus; protein sumoylation; regulation of cellular response to heat; regulation of gene silencing by miRNA; regulation of glycolytic process; tRNA export from nucleus; viral process; viral transcription
Reference #:  A8CG34 (UniProtKB)
Alt. Names/Synonyms: DKFZp586P2220; DKFZp779K1713; FLJ43877; FLJ45082; MGC163459; MGC163461; Nuclear envelope pore membrane protein POM 121C; Nuclear pore membrane protein 121-2; P121C; POM121 membrane glycoprotein C; POM121 membrane glycoprotein-like; POM121 transmembrane nucleoporin C; POM121-2; POM121C; Pore membrane protein of 121 kDa C
Gene Symbols: POM121C
Molecular weight: 125,059 Da
Basal Isoelectric point: 10.38  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene