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ME2
Belongs to the malic enzymes family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Carbohydrate Metabolism - pyruvate; EC 1.1.1.38; Mitochondrial; Oxidoreductase |
| Chromosomal Location of human Ortholog: 18q21.2 |
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Cellular Component:
intracellular membrane-bounded organelle; mitochondrial matrix; mitochondrion
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Molecular Function:
electron transfer activity; malate dehydrogenase (decarboxylating) (NAD+) activity; malate dehydrogenase (decarboxylating) (NADP+) activity; malic enzyme activity; metal ion binding; NAD binding; oxaloacetate decarboxylase activity
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Biological Process:
electron transport chain; malate metabolic process; pyruvate metabolic process; regulation of NADP metabolic process
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Disease: Epilepsy, Idiopathic Generalized; Opioid Dependence, Susceptibility To, 1
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Reference #:
P23368
(UniProtKB)
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Alt. Names/Synonyms: malate dehydrogenase (oxaloacetate-decarboxylating); Malic enzyme 2; malic enzyme 2, NAD(+)-dependent, mitochondrial; MAOM; ME2; NAD-dependent malic enzyme, mitochondrial; NAD-ME; ODS1; pyruvic-malic carboxylase
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Gene Symbols: ME2
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Molecular weight:
65,444 Da
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Basal Isoelectric point:
7.52
Predict pI for various phosphorylation states
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CST Pathways:
Warburg Effect
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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