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PSME3IP1
Promotes the association of the proteasome activator complex subunit PSME3 with the 20S proteasome and regulates its activity. Inhibits PSME3-mediated degradation of some proteasome substrates, probably by affecting their diffusion rate into the catalytic chamber of the proteasome. Also inhibits the interaction of PSME3 with COIL, inhibits accumulation of PSME3 in Cajal bodies and positively regulates the number of Cajal bodies in the nucleus. Note: This description may include information from UniProtKB.
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| Protein type: Unknown function |
| Chromosomal Location of Human Ortholog: 8|8 C5 |
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Cellular Component:
nucleus
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Biological Process:
negative regulation of proteasomal protein catabolic process; negative regulation of protein binding
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Reference #:
Q91WE2
(UniProtKB)
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Alt. Names/Synonyms: 1700001O11Rik; 2310065K24Rik; AI596259; F192A; Fam19; Fam192a; family with sequence similarity 192, member A; NEFA-interacting nuclear protein NIP30; Nip30; PA28G-interacting protein; PIP30; proteasome activator subunit 3 interacting protein 1; Protein FAM192A; PSME3-interacting protein; Psme3ip1
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Gene Symbols: Psme3ip1
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Molecular weight:
28,702 Da
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Basal Isoelectric point:
5.08
Predict pI for various phosphorylation states
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