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SKIV2L2
May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily. Note: This description may include information from UniProtKB.
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| Protein type: DNA-binding; EC 3.6.4.13; Helicase; Nucleolus; Spliceosome |
| Chromosomal Location of Human Ortholog: 13|13 D2.2 |
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Cellular Component:
catalytic step 2 spliceosome; exosome (RNase complex); nucleus; spliceosomal complex
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Molecular Function:
ATP binding; ATP-dependent RNA helicase activity; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; RNA binding; RNA helicase activity
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Biological Process:
maturation of 5.8S rRNA; mRNA processing; RNA catabolic process; RNA splicing; rRNA processing
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Reference #:
Q9CZU3
(UniProtKB)
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Alt. Names/Synonyms: 2610528A15Rik; ATP-dependent helicase SKIV2L2; Exosome RNA helicase MTR4; mKIAA0052; SK2L2; Skiv2l2; Superkiller viralicidic activity 2-like 2; superkiller viralicidic activity 2-like 2 (S. cerevisiae)
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Gene Symbols: Skiv2l2
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Molecular weight:
117,636 Da
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Basal Isoelectric point:
6.01
Predict pI for various phosphorylation states
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