SKIV2L2 May be involved in pre-mRNA splicing. Associated with the RNA exosome complex and involved in the 3'processing of the 7S pre-RNA to the mature 5.8S rRNA. Belongs to the helicase family. SKI2 subfamily. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; EC 3.6.4.13; Helicase; Nucleolus; Spliceosome
Chromosomal Location of Human Ortholog: 13|13 D2.2
Cellular Component:  catalytic step 2 spliceosome; exosome (RNase complex); nucleus; spliceosomal complex
Molecular Function:  ATP binding; ATP-dependent RNA helicase activity; helicase activity; hydrolase activity; nucleic acid binding; nucleotide binding; RNA binding; RNA helicase activity
Biological Process:  maturation of 5.8S rRNA; mRNA processing; RNA catabolic process; RNA splicing; rRNA processing
Reference #:  Q9CZU3 (UniProtKB)
Alt. Names/Synonyms: 2610528A15Rik; ATP-dependent helicase SKIV2L2; Exosome RNA helicase MTR4; mKIAA0052; SK2L2; Skiv2l2; Superkiller viralicidic activity 2-like 2; superkiller viralicidic activity 2-like 2 (S. cerevisiae)
Gene Symbols: Skiv2l2
Molecular weight: 117,636 Da
Basal Isoelectric point: 6.01  Predict pI for various phosphorylation states
Select Structure to View Below

SKIV2L2

Protein Structure Not Found.


Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene