PMPCA Cleaves presequences (transit peptides) from mitochondrial protein precursors. Belongs to the peptidase M16 family. Note: This description may include information from UniProtKB.
Protein type: EC; Mitochondrial; Protease
Chromosomal Location of Human Ortholog: 2|2 A3
Cellular Component:  membrane; mitochondrial inner membrane; mitochondrion
Molecular Function:  catalytic activity; endopeptidase activity; hydrolase activity; metal ion binding; metalloendopeptidase activity; metallopeptidase activity; peptidase activity
Biological Process:  protein processing; protein processing involved in protein targeting to mitochondrion; proteolysis
Reference #:  Q9DC61 (UniProtKB)
Alt. Names/Synonyms: 1200002L24Rik; 4933435E07Rik; Alpha-MPP; mitochondrial matrix processing protease, alpha subunit; Mitochondrial-processing peptidase subunit alpha; OTTMUSP00000013720; P-55; peptidase (mitochondrial processing) alpha; Pmpca
Gene Symbols: Pmpca
Molecular weight: 58,279 Da
Basal Isoelectric point: 6.36  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein