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RPS23
Component of the ribosome, a large ribonucleoprotein complex responsible for the synthesis of proteins in the cell. The small ribosomal subunit (SSU) binds messenger RNAs (mRNAs) and translates the encoded message by selecting cognate aminoacyl-transfer RNA (tRNA) molecules. The large subunit (LSU) contains the ribosomal catalytic site termed the peptidyl transferase center (PTC), which catalyzes the formation of peptide bonds, thereby polymerizing the amino acids delivered by tRNAs into a polypeptide chain. The nascent polypeptides leave the ribosome through a tunnel in the LSU and interact with protein factors that function in enzymatic processing, targeting, and the membrane insertion of nascent chains at the exit of the ribosomal tunnel. Plays an important role in translational accuracy. Belongs to the universal ribosomal protein uS12 family. Note: This description may include information from UniProtKB.
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| Protein type: Ribosomal; Translation |
| Chromosomal Location of mouse Ortholog: 13|13 C3 |
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Cellular Component:
cytoplasm; cytosol; cytosolic ribosome; cytosolic small ribosomal subunit; endoplasmic reticulum; nucleus; polysomal ribosome; postsynapse; ribonucleoprotein complex; ribosome; small ribosomal subunit; small-subunit processome; synapse
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Molecular Function:
protein binding; structural constituent of ribosome
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Biological Process:
cytoplasmic translation; maintenance of translational fidelity; ribosomal small subunit biogenesis; stress granule assembly; translation
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Reference #:
P62267
(UniProtKB)
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Alt. Names/Synonyms: 2410044J15Rik; 40S ribosomal protein S23; ribosomal protein S23; Rps23; RS23; Small ribosomal subunit protein uS12
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Gene Symbols: Rps23
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Molecular weight:
15,808 Da
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Basal Isoelectric point:
10.5
Predict pI for various phosphorylation states
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