PPIL2 a peptidylprolyl isomerase (PPIase) of the cyclophilin-type family. PPIases accelerate the folding of proteins by catalyzing the cis-trans isomerization of proline imidic peptide bonds. Two alternatively-spliced isoforms have been described. Note: This description may include information from UniProtKB.
Protein type: Cyclophilin; EC; Isomerase; Ligase; Spliceosome; Ubiquitin conjugating system; Ubiquitin ligase
Chromosomal Location of Human Ortholog: 16|16 A3
Cellular Component:  cytoplasm; nucleoplasm; nucleus; plasma membrane
Molecular Function:  peptidyl-prolyl cis-trans isomerase activity; transferase activity; ubiquitin protein ligase activity; ubiquitin-protein transferase activity; ubiquitin-ubiquitin ligase activity
Biological Process:  protein folding; protein localization to plasma membrane; protein peptidyl-prolyl isomerization; protein polyubiquitination; protein ubiquitination
Reference #:  Q9D787 (UniProtKB)
Alt. Names/Synonyms: 0610009L05Rik; 1700016N17Rik; 4921520K19Rik; 4930511F14Rik; AA589416; C130078A06Rik; Cyclophilin-60; Cyclophilin-like protein Cyp-60; OTTMUSP00000028554; OTTMUSP00000028555; Peptidyl-prolyl cis-trans isomerase-like 2; peptidylprolyl isomerase (cyclophilin)-like 2; Ppil2; Rotamase PPIL2
Gene Symbols: Ppil2
Molecular weight: 59,065 Da
Basal Isoelectric point: 8.59  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  Reactome  |  BioGPS  |  Pfam  |  ENZYME  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene