GNPDA1 Seems to trigger calcium oscillations in mammalian eggs. These oscillations serve as the essential trigger for egg activation and early development of the embryo. Belongs to the glucosamine/galactosamine-6-phosphate isomerase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Carbohydrate Metabolism - amino sugar and nucleotide sugar; EC; Hydrolase; Isomerase
Chromosomal Location of human Ortholog: 5q31.3
Cellular Component:  cytoplasm; cytosol
Molecular Function:  glucosamine-6-phosphate deaminase activity; protein binding
Biological Process:  carbohydrate metabolic process; generation of precursor metabolites and energy; glucosamine catabolic process; single fertilization
Reference #:  P46926 (UniProtKB)
Alt. Names/Synonyms: GlcN6P deaminase 1; Glucosamine-6-phosphate deaminase 1; Glucosamine-6-phosphate isomerase 1; GNP1; GNPDA; GNPDA 1; GNPDA1; GNPI; GNPI1; GPI; HLN; KIAA0060; Oscillin
Gene Symbols: GNPDA1
Molecular weight: 32,669 Da
Basal Isoelectric point: 6.42  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  RCSB PDB  |  ENZYME  |  Phospho3D  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene