SMC2L1
Central component of the condensin complex, a complex required for conversion of interphase chromatin into mitotic-like condense chromosomes. The condensin complex probably introduces positive supercoils into relaxed DNA in the presence of type I topoisomerases and converts nicked DNA into positive knotted forms in the presence of type II topoisomerases. Belongs to the SMC family. SMC2 subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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Protein type: Cell cycle regulation |
Chromosomal Location of mouse Ortholog: 4 B2|4 28.31 cM |
Cellular Component:
chromatin; chromosome; condensed chromosome; condensed nuclear chromosome; condensin complex; cytoplasm; nuclear chromosome; nucleolus; nucleoplasm; nucleus
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Molecular Function:
ATP binding; ATP hydrolysis activity; chromatin binding; nucleotide binding; protein binding; single-stranded DNA binding
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Biological Process:
cell cycle; cell division; chromosome condensation; chromosome organization; kinetochore organization; meiotic chromosome condensation; meiotic chromosome segregation; mitotic chromosome condensation; positive regulation of chromosome condensation; positive regulation of chromosome segregation; positive regulation of chromosome separation; single strand break repair
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Reference #:
Q8CG48
(UniProtKB)
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Alt. Names/Synonyms: 5730502P04Rik; AI255214; AW545314; CAP; CAP-E; Cape; Chromosome-associated protein E; FGF-inducible protein 16; fibroblast growth factor inducible 16; Fin; Fin16; OTTMUSP00000007454; SMC protein 2; SMC-2; Smc2; SMC2 structural maintenance of chromosomes 2-like 1; Smc2l1; structural maintenance of chromosomes 2; Structural maintenance of chromosomes protein 2; XCAP-E homolog
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Gene Symbols: Smc2
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Molecular weight:
134,239 Da
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Basal Isoelectric point:
8.54
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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