ATP5I
Mitochondrial membrane ATP synthase (F(1)F(0) ATP synthase or Complex V) produces ATP from ADP in the presence of a proton gradient across the membrane which is generated by electron transport complexes of the respiratory chain. F-type ATPases consist of two structural domains, F(1) - containing the extramembraneous catalytic core, and F(0) - containing the membrane proton channel, linked together by a central stalk and a peripheral stalk. During catalysis, ATP synthesis in the catalytic domain of F(1) is coupled via a rotary mechanism of the central stalk subunits to proton translocation. Part of the complex F(0) domain. Minor subunit located with subunit a in the membrane. Belongs to the ATPase e subunit family. Note: This description may include information from UniProtKB.
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Protein type: EC 3.6.3.14; Energy Metabolism - oxidative phosphorylation; Mitochondrial |
Chromosomal Location of mouse Ortholog: 5 F|5 53.11 cM |
Cellular Component:
membrane; mitochondrial inner membrane; mitochondrial proton-transporting ATP synthase complex; mitochondrial proton-transporting ATP synthase complex, coupling factor F(o); mitochondrion; proton-transporting ATP synthase complex, coupling factor F(o)
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Molecular Function:
protein-containing complex binding; proton transmembrane transporter activity; proton-transporting ATP synthase activity, rotational mechanism
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Biological Process:
ATP biosynthetic process; monoatomic ion transport; proton motive force-driven ATP synthesis; proton motive force-driven mitochondrial ATP synthesis; proton transmembrane transport
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Reference #:
Q06185
(UniProtKB)
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Alt. Names/Synonyms: 2610008D24Rik; ATP synthase membrane subunit e; ATP synthase subunit e, mitochondrial; ATP synthase, H+ transporting, mitochondrial F1F0 complex, subunit e; Atp5i; Atp5k; Atp5me; ATPase subunit e; Lfm; Lfm-1; Lfm1; MGC107302
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Gene Symbols: Atp5me
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Molecular weight:
8,236 Da
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Basal Isoelectric point:
9.34
Predict pI for various phosphorylation states
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