SAMD4B Has transcriptional repressor activity. Overexpression inhibits the transcriptional activities of AP-1, p53/TP53 and CDKN1A. Belongs to the SMAUG family. Widely expressed in embryonic and adult tissues. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 1q21
Cellular Component:  cytosol; P-body
Molecular Function:  mRNA binding; translation repressor activity
Biological Process:  cerebellar neuron development; negative regulation of translation; nuclear-transcribed mRNA poly(A) tail shortening; regulation of mRNA stability
Reference #:  NP_001100968 (RefSeq)
Alt. Names/Synonyms: RGD1305597; Samd4b; sterile alpha motif domain containing 4B
Gene Symbols: Samd4b
Molecular weight: 74,912 Da
Basal Isoelectric point: 6.46  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  BioGPS  |  Entrez-Gene  |  GenPept  |  Ensembl Gene