HSPB8 Displays temperature-dependent chaperone activity. Belongs to the small heat shock protein (HSP20) family. Predominantly expressed in skeletal muscle and heart. Note: This description may include information from UniProtKB.
Protein type: Heat shock protein
Chromosomal Location of rat Ortholog: 12q16
Cellular Component:  chaperone complex; cytoplasm; cytosol; nuclear body; nucleoplasm; nucleus
Molecular Function:  identical protein binding; protein homodimerization activity; protein kinase activity
Biological Process:  cellular response to unfolded protein; positive regulation of aggrephagy
Reference #:  Q9EPX0 (UniProtKB)
Alt. Names/Synonyms: Alpha-crystallin C chain; Cryac; crystallin, alpha C; heat shock 22kDa protein 8; heat shock protein 8; heat shock protein B8; Heat shock protein beta-8; Hsp22; HspB8; MGC72354; Small stress protein-like protein HSP22
Gene Symbols: Hspb8
Molecular weight: 21,592 Da
Basal Isoelectric point: 4.92  Predict pI for various phosphorylation states
Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology® Total Proteins
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Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene