P311 May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration. May also have functions in cellular differentiation. Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. Expressed in lung (at protein level). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Motility/polarity/chemotaxis
Chromosomal Location of Human Ortholog: 5q22.1
Cellular Component: 
Molecular Function:  protein binding
Reference #:  Q16612 (UniProtKB)
Alt. Names/Synonyms: C5orf13; chromosome 5 open reading frame 13; D4S114; Neuronal protein 3.1; neuronal regeneration related protein; neuronal regeneration related protein homolog; Neuronal regeneration-related protein; NP311; NREP; P311; PRO1873; Protein p311; PTZ17; SEZ17
Gene Symbols: NREP
Molecular weight: 7,909 Da
Basal Isoelectric point: 9.16  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein