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P311
May have roles in neural function. Ectopic expression augments motility of gliomas. Promotes also axonal regeneration. May also have functions in cellular differentiation. Induces differentiation of fibroblast into myofibroblast and myofibroblast ameboid migration. Increases retinoic-acid regulation of lipid-droplet biogenesis. Down-regulates the expression of TGFB1 and TGFB2 but not of TGFB3. May play a role in the regulation of alveolar generation. Expressed in lung (at protein level). 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Motility/polarity/chemotaxis |
| Chromosomal Location of Human Ortholog: 5q22.1 |
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Cellular Component:
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Molecular Function:
protein binding
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Reference #:
Q16612
(UniProtKB)
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Alt. Names/Synonyms: C5orf13; chromosome 5 open reading frame 13; D4S114; Neuronal protein 3.1; Neuronal regeneration-related protein; NP311; P311; PRO1873; Protein p311; PTZ17
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Gene Symbols: NREP
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Molecular weight:
7,909 Da
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Basal Isoelectric point:
9.16
Predict pI for various phosphorylation states
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