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Sialoprotein-2
Binds tightly to hydroxyapatite. Appears to form an integral part of the mineralized matrix. Probably important to cell-matrix interaction. Promotes Arg-Gly-Asp-dependent cell attachment. Note: This description may include information from UniProtKB.
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| Protein type: Cell adhesion; Motility/polarity/chemotaxis; Secreted; Secreted, signal peptide |
| Chromosomal Location of human Ortholog: 4q22.1 |
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Cellular Component:
extracellular region; extracellular space; vesicle
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Molecular Function:
integrin binding; protein binding; small molecule binding
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Biological Process:
bone mineralization; cell adhesion; cellular response to growth factor stimulus; extracellular matrix organization; positive regulation of cell adhesion
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Reference #:
P21815
(UniProtKB)
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Alt. Names/Synonyms: BNSP; Bone sialoprotein 2; Bone sialoprotein II; BSP; BSP II; BSP-II; Cell-binding sialoprotein; IBSP; integrin binding sialoprotein; Integrin-binding sialoprotein; SIAL; Sialoprotein-2; SP-II
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Gene Symbols: IBSP
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Molecular weight:
35,148 Da
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Basal Isoelectric point:
4.14
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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