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ADH1B
Belongs to the zinc-containing alcohol dehydrogenase family. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - tyrosine; Carbohydrate Metabolism - glycolysis and gluconeogenesis; Cofactor and Vitamin Metabolism - retinol; EC 1.1.1.1; Lipid Metabolism - fatty acid; Oxidoreductase; Xenobiotic Metabolism - drug metabolism - cytochrome P450; Xenobiotic Metabolism - metabolism by cytochrome P450 |
| Chromosomal Location of human Ortholog: 4q23 |
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Cellular Component:
cytosol; nucleoplasm; plasma membrane
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Molecular Function:
alcohol dehydrogenase activity, zinc-dependent; NAD-retinol dehydrogenase activity; zinc ion binding
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Biological Process:
ethanol oxidation; retinoic acid metabolic process; retinoid metabolic process; retinol metabolic process
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Disease: Alcohol Dependence
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Reference #:
P00325
(UniProtKB)
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Alt. Names/Synonyms: ADH, beta subunit; ADH1B; ADH2; Alcohol dehydrogenase 1B; alcohol dehydrogenase 1B (class I), beta polypeptide; alcohol dehydrogenase 2 (class I), beta polypeptide; Alcohol dehydrogenase subunit beta; aldehyde reductase; All-trans-retinol dehydrogenase [NAD(+)] ADH1B; DKFZp686C06125; epididymis secretory protein Li 117; HEL-S-117
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Gene Symbols: ADH1B
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Molecular weight:
39,835 Da
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Basal Isoelectric point:
8.53
Predict pI for various phosphorylation states
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Protein-Specific Antibodies, siRNAs or Recombinant Proteins from Cell Signaling Technology®
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