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URB
Promotes cell adhesion and matrix assembly. Belongs to the CCDC80 family. Expressed in dermal papilla and dermal fibroblasts (at protein level). Expressed in heart, thymus, placenta, pancreas, colon, epithelium, spleen and osteoblasts. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
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| Protein type: Extracellular matrix; Secreted; Secreted, signal peptide |
| Chromosomal Location of mouse Ortholog: 16|16 B5 |
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Cellular Component:
basement membrane; extracellular matrix; extracellular region; interstitial matrix
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Molecular Function:
fibronectin binding; glycosaminoglycan binding; heparin binding
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Biological Process:
extracellular matrix organization; positive regulation of cell-substrate adhesion; response to bacterium
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Reference #:
Q8R2G6
(UniProtKB)
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Alt. Names/Synonyms: 2610001E17Rik; CCD80; Ccdc80; coiled-coil domain containing 80; Coiled-coil domain-containing protein 80; DRO1; OTTMUSP00000030743; Ssg1; steroid sensitive gene 1; Up-regulated in BRS-3 deficient mouse; Urb
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Gene Symbols: Ccdc80
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Molecular weight:
107,613 Da
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Basal Isoelectric point:
9.59
Predict pI for various phosphorylation states
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