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AGMAT
Belongs to the arginase family. Agmatinase subfamily. Highly expressed in liver and kidney. Also found in skeletal muscle, fetal liver, brain, testis, skin and the gastrointestinal tract. Within brain, expression is higher in the cerebral cortex with lower levels in the medulla and spinal cord. Note: This description may include information from UniProtKB.
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| Protein type: Amino Acid Metabolism - arginine and proline; EC 3.5.3.11; Hydrolase |
| Chromosomal Location of mouse Ortholog: 4|4 E1 |
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Cellular Component:
mitochondrion
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Molecular Function:
agmatinase activity; arginase activity; guanidinobutyrase activity; guanidinopropionase activity; hydrolase activity; metal ion binding
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Biological Process:
putrescine biosynthetic process; putrescine biosynthetic process from arginine, using agmatinase; spermidine biosynthetic process
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Reference #:
A2AS89
(UniProtKB)
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Alt. Names/Synonyms: 5033405N08Rik; Agmat; Agmatinase, mitochondrial; Agmatine ureohydrolase; agmatine ureohydrolase (agmatinase); AUH; Guanidino acid hydrolase, mitochondrial; OTTMUSP00000010524; SPEB
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Gene Symbols: Agmat
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Molecular weight:
38,255 Da
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Basal Isoelectric point:
8.07
Predict pI for various phosphorylation states
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