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ARHGAP15
GTPase activator for the Rho-type GTPases by converting them to an inactive GDP-bound state. Has activity toward RAC1. Overexpression results in an increase in actin stress fibers and cell contraction. Expressed in lung, liver and lymphoid cells. Note: This description may include information from UniProtKB.
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| Protein type: GAP; GAP, Rac/Rho |
| Chromosomal Location of mouse Ortholog: 2|2 B |
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Cellular Component:
cytoplasm; membrane
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Molecular Function:
GTPase activator activity
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Biological Process:
regulation of cell shape; regulation of GTPase activity; signal transduction
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Reference #:
Q811M1
(UniProtKB)
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Alt. Names/Synonyms: 5830480G12Rik; ArhGAP15; OTTMUSP00000013237; RHG15; Rho GTPase activating protein 15; Rho GTPase-activating protein 15; Rho-type GTPase-activating protein 15
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Gene Symbols: Arhgap15
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Molecular weight:
55,339 Da
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Basal Isoelectric point:
9.25
Predict pI for various phosphorylation states
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