LUZP5 Regulatory subunit of the condensin-2 complex, a complex which establishes mitotic chromosome architecture and is involved in physical rigidity of the chromatid axis. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 7q36.3
Cellular Component:  condensin complex; nuclear speck; nucleoplasm
Molecular Function:  bHLH transcription factor binding; methylated histone binding; molecular function regulator; protein binding
Biological Process:  cell cycle; cell division; chromosome condensation; erythrocyte differentiation; inner cell mass cell proliferation; negative regulation of erythrocyte differentiation; positive regulation of protein tyrosine kinase activity; positive regulation of signaling receptor activity; transcription by RNA polymerase II
Disease: Khan-khan-katsanis Syndrome
Reference #:  Q86XI2 (UniProtKB)
Alt. Names/Synonyms: 3KS; CAP-G2; CAPG2; Chromosome-associated protein G2; CNDG2; Condensin-2 complex subunit G2; FLJ20311; hCAP-G2; Leucine zipper protein 5; LUZP5; more than blood homolog; MTB; NCAPG2; Non-SMC condensin II complex subunit G2; non-SMC condensin II complex, subunit G2
Gene Symbols: NCAPG2
Molecular weight: 130,960 Da
Basal Isoelectric point: 6.43  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene