TMEM63A Acts as an osmosensitive calcium-permeable cation channel. Belongs to the CSC1 (TC 1.A.17) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of mouse Ortholog: 1|1 H4
Cellular Component:  centriolar satellite; intracellular membrane-bounded organelle; lysosomal membrane; lysosome; membrane; plasma membrane
Molecular Function:  calcium activated cation channel activity; mechanosensitive monoatomic ion channel activity; nucleic acid binding; osmolarity-sensing monoatomic cation channel activity
Biological Process:  monoatomic ion transport
Reference #:  Q91YT8 (UniProtKB)
Alt. Names/Synonyms: BC014795; CSC1-like protein 1; CSCL1; Kiaa0792; MGC11687; MGC25803; TM63A; Tmem63a; Tmem64a; Transmembrane protein 63A
Gene Symbols: Tmem63a
Molecular weight: 91,860 Da
Basal Isoelectric point: 8.26  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

Cross-references to other databases:  AlphaFold  |  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein