TMEM63A Acts as an osmosensitive calcium-permeable cation channel. Belongs to the CSC1 (TC 1.A.17) family. Note: This description may include information from UniProtKB.
Protein type: Membrane protein, integral; Membrane protein, multi-pass
Chromosomal Location of Human Ortholog: 1q42.12
Cellular Component:  integral component of membrane; intracellular membrane-bounded organelle; lysosomal membrane; microtubule organizing center; plasma membrane; specific granule membrane; tertiary granule membrane
Molecular Function:  nucleic acid binding
Biological Process:  ion transmembrane transport; neutrophil degranulation
Disease: Leukodystrophy, Hypomyelinating, 19, Transient Infantile
Reference #:  O94886 (UniProtKB)
Alt. Names/Synonyms: CSC1-like protein 1; CSCL1; HLD19; KIAA0489; KIAA0792; TM63A; TMEM63A; Transmembrane protein 63A
Gene Symbols: TMEM63A
Molecular weight: 92,126 Da
Basal Isoelectric point: 6.98  Predict pI for various phosphorylation states
Select Structure to View Below

TMEM63A

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene