TMEM63A
Acts as an osmosensitive calcium-permeable cation channel. Belongs to the CSC1 (TC 1.A.17) family. Note: This description may include information from UniProtKB.
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Protein type: Membrane protein, integral; Membrane protein, multi-pass |
Chromosomal Location of human Ortholog: 1q42.12 |
Cellular Component:
centriolar satellite; intracellular membrane-bounded organelle; lysosomal membrane; plasma membrane; specific granule membrane; tertiary granule membrane
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Molecular Function:
calcium activated cation channel activity; mechanosensitive monoatomic ion channel activity; nucleic acid binding; osmolarity-sensing monoatomic cation channel activity; protein binding
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Biological Process:
monoatomic cation transmembrane transport
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Disease: Leukodystrophy, Hypomyelinating, 19, Transient Infantile
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Reference #:
O94886
(UniProtKB)
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Alt. Names/Synonyms: CSC1-like protein 1; CSCL1; HLD19; KIAA0489; KIAA0792; TM63A; TMEM63A; Transmembrane protein 63A
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Gene Symbols: TMEM63A
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Molecular weight:
92,126 Da
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Basal Isoelectric point:
6.98
Predict pI for various phosphorylation states
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