VPS13C Necessary for proper mitochondrial function and maintenance of mitochondrial transmembrane potential. Involved in the regulation of PINK1/PRKN-mediated mitophagy in response to mitochondrial depolarization. Belongs to the VPS13 family. Widely expressed. 4 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Unknown function
Chromosomal Location of Human Ortholog: 9|9 C
Cellular Component:  cytosol; extrinsic component of membrane; membrane; mitochondrial outer membrane; mitochondrion
Biological Process:  mitochondrion organization; negative regulation of parkin-mediated stimulation of mitophagy in response to mitochondrial depolarization; protein retention in Golgi apparatus; protein targeting to vacuole
Reference #:  Q8BX70 (UniProtKB)
Alt. Names/Synonyms: AI552542; AV026040; C230055H22Rik; chorein; Kiaa3021; vacuolar protein sorting 13C; vacuolar protein sorting 13C (yeast); Vacuolar protein sorting-associated protein 13C; VP13C; Vps13c; vps13c 5' variant II; vps13c 5' variant III; Vps13c 5' variant VI; W51662
Gene Symbols: Vps13c
Molecular weight: 420,089 Da
Basal Isoelectric point: 6.37  Predict pI for various phosphorylation states
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Protein Structure Not Found.

Cross-references to other databases:  STRING  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  UniProtKB  |  Entrez-Gene  |  Ensembl Gene