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HBA1
Involved in oxygen transport from the lung to the various peripheral tissues. Belongs to the globin family. Red blood cells. Note: This description may include information from UniProtKB.
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| Protein type: Carrier |
| Chromosomal Location of Human Ortholog: 16p13.3 |
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Cellular Component:
cytosol; cytosolic small ribosomal subunit; endocytic vesicle lumen; extracellular region; extracellular space; haptoglobin-hemoglobin complex; hemoglobin complex
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Molecular Function:
iron ion binding; protein binding
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Biological Process:
bicarbonate transport; cellular oxidant detoxification; hydrogen peroxide catabolic process; oxygen transport; positive regulation of cell death; protein heterooligomerization; receptor-mediated endocytosis; response to hydrogen peroxide
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Disease: Alpha-thalassemia; Erythrocytosis, Familial, 7; Heinz Body Anemias; Hemoglobin H Disease; Methemoglobinemia, Alpha Type
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Reference #:
P69905
(UniProtKB)
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Alt. Names/Synonyms: alpha globin chain; alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; CD31; delta globin; ECYT7; HBA; HBA-T3; HBA1; HBA2; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; hemoglobin alpha-1 chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1; METHBA; MGC126895; MGC126897
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Gene Symbols: HBA1; HBA2
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Molecular weight:
15,258 Da
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Basal Isoelectric point:
8.72
Predict pI for various phosphorylation states
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