HBA1 Involved in oxygen transport from the lung to the various peripheral tissues. Belongs to the globin family. Red blood cells. Note: This description may include information from UniProtKB.
Protein type: Carrier
Chromosomal Location of Human Ortholog: 16p13.3
Cellular Component:  cytosol; cytosolic small ribosomal subunit; endocytic vesicle lumen; extracellular region; extracellular space; haptoglobin-hemoglobin complex; hemoglobin complex
Molecular Function:  iron ion binding; protein binding
Biological Process:  bicarbonate transport; cellular oxidant detoxification; hydrogen peroxide catabolic process; oxygen transport; positive regulation of cell death; protein heterooligomerization; receptor-mediated endocytosis; response to hydrogen peroxide
Disease: Alpha-thalassemia; Erythrocytosis, Familial, 7; Heinz Body Anemias; Hemoglobin H Disease; Methemoglobinemia, Alpha Type
Reference #:  P69905 (UniProtKB)
Alt. Names/Synonyms: alpha globin chain; alpha one globin; alpha-1 globin; alpha-1-globin; alpha-2 globin chain; Alpha-globin; CD31; delta globin; ECYT7; HBA; HBA-T3; HBA1; HBA2; HBH; hemoglobin alpha 1 globin chain; Hemoglobin alpha chain; hemoglobin alpha-1 chain; Hemoglobin subunit alpha; hemoglobin subunit alpha 1; hemoglobin, alpha 1; METHBA; MGC126895; MGC126897
Gene Symbols: HBA1; HBA2
Molecular weight: 15,258 Da
Basal Isoelectric point: 8.72  Predict pI for various phosphorylation states
Select Structure to View Below


Protein Structure Not Found.

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