ABCC9 Subunit of ATP-sensitive potassium channels (KATP). Can form cardiac and smooth muscle-type KATP channels with KCNJ11. KCNJ11 forms the channel pore while ABCC9 is required for activation and regulation. Belongs to the ABC transporter superfamily. ABCC family. Conjugate transporter (TC 3.A.1.208) subfamily. 2 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: Channel, potassium; Membrane protein, integral; Membrane protein, multi-pass; Transporter; Transporter, ABC family
Chromosomal Location of Human Ortholog: 12p12.1
Cellular Component:  inward rectifying potassium channel; plasma membrane; sarcomere
Molecular Function:  ATP binding; ion channel binding; potassium channel regulator activity; sulfonylurea receptor activity
Biological Process:  defense response to virus; potassium ion import across plasma membrane; regulation of cardiac conduction; transmembrane transport
Disease: Atrial Fibrillation, Familial, 12; Cantu Syndrome; Cardiomyopathy, Dilated, 1o
Reference #:  O60706 (UniProtKB)
Alt. Names/Synonyms: ABC37; ABCC9; ATP-binding cassette sub-family C member 9; ATP-binding cassette transporter sub-family C member 9; ATP-binding cassette, sub-family C (CFTR/MRP), member 9; CMD1O; FLJ36852; Sulfonylurea receptor 2; sulfonylurea receptor 2A; SUR2
Gene Symbols: ABCC9
Molecular weight: 174,224 Da
Basal Isoelectric point: 7.05  Predict pI for various phosphorylation states
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ABCC9

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  Reactome  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  InnateDB  |  Ensembl Protein