HAUS7 Contributes to mitotic spindle assembly, maintenance of centrosome integrity and completion of cytokinesis as part of the HAUS augmin-like complex. Belongs to the HAUS7 family. Detected in spleen, thymus, testis, ovary, small intestine and colon, with highest levels of expression in testis and ovary. 3 alternatively spliced human isoforms have been reported. Note: This description may include information from UniProtKB.
Protein type: DNA-binding; Deoxyribonuclease; EC 3.1.11.2
Chromosomal Location of Human Ortholog: Xq28
Cellular Component:  centrosome; cytosol; HAUS complex; microtubule; spindle
Molecular Function:  protein binding; thioesterase binding
Biological Process:  cell division; centrosome cycle; ciliary basal body-plasma membrane docking; G2/M transition of mitotic cell cycle; regulation of G2/M transition of mitotic cell cycle; spindle assembly
Reference #:  Q99871 (UniProtKB)
Alt. Names/Synonyms: 26S proteasome-associated UCH interacting protein 1; 26S proteasome-associated UCH37-interacting protein 1; expressed-Xq28STS protein; HAUS augmin like complex subunit 7; HAUS augmin-like complex subunit 7; HAUS augmin-like complex, subunit 7; HAUS7; HSXQ28ORF; UCH37 interacting protein 1; UCHL5 interacting protein; UCHL5-interacting protein; UCHL5IP; UIP1; X-linked protein STS1769
Gene Symbols: HAUS7
Molecular weight: 40,778 Da
Basal Isoelectric point: 4.73  Predict pI for various phosphorylation states
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HAUS7

Protein Structure Not Found.

Cross-references to other databases:  STRING  |  cBioPortal  |  Wikipedia  |  neXtProt  |  Protein Atlas  |  BioGPS  |  Pfam  |  Phospho.ELM  |  NetworKIN  |  GeneCards  |  UniProtKB  |  Entrez-Gene  |  GenPept  |  Ensembl Gene  |  Ensembl Protein